The following is a partial list of peer-reviewed publications based on work funded by the National Research Fund for Tick-Borne Diseases. Each of the publications in this list explicitly acknowledges NRFTD support.
Hawley KL, Olson CM, Iglesias-Pedraz JM, et al. CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1228-32 http://www.ncbi.nlm.nih.gov/pubmed/22232682
Dunham-Ems SM, Caimano MJ, Eggers CH and Radolf JD. Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission. PLoS Pathog. 2012 February; 8(2): e1002532 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280991
Eggers CH, Caimano MJ, Malizia RA, et al. The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host. Mol Microbiol. 2011 Nov;82(3):679-97. http://www.ncbi.nlm.nih.gov/pubmed/21923763
Pappas CJ, Iyer R, Petzke MM, et al. Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle. PLoS Pathog. 2011 July; 7(7): e1002102. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131272
Caimano MJ, Kenedy MR, Kairu T, et al. The hybrid histidine kinase Hk1 Is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun. 2011 August; 79(8): 3117–3130. http://www.ncbi.nlm.nih.gov/pubmed/21606185
Banik S, Terekhova D, Iyer R, et al. BB0844, an RpoS-regulated protein, is dispensable for Borrelia burgdorferi infectivity and maintenance in the mouse-tick infectious cycle. Infect Immun. 2010 Dec 20 [Epub ahead of print]
Barthold SA, Hodzic, Imai DM, et al. Ineffectiveness of tigecycline against persistent Borrelia burgdorferi. Antimicrob Agents Chemother. 2010;54(2): 643-51.
Huang B, Troese MJ, Howe D, et al. Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane. Microb Pathog. 2010; 49(5): 273-84.
Huang B, Hubber A, McDonough JA, et al. The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes. Cell Microbiol. 2010; 12(9): 1292-307.
Huang B, Troese MY, Ye S, et al. Anaplasma phagocytophilum APH_1387 is expressed throughout bacterial intracellular development and localizes to the pathogen-occupied vacuolar membrane. Infect Immun. 2010; 78(5): 1864–73.
XU H, Caimano MJ, Lin T, et al. Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi. PLoS Pathog. 2010; 6(9): e1001104.
Dunham-Ems SM, Caimano MJ, Pal U, et al. Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks. J Clin Invest. 2009; 119(12): 3652-65.
Grab DJ, Nyarko E, Nikolskaia OV, et al. Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling. Clin Microbiol Infect. 2009; 15(5): 422-6.
Saidac DS, Marras SAE, Parveen N. Detection and quantification of Lyme spirochetes using sensitive and specific molecular beacon probes. BMC Microbiol. 2009; 9: 43.
Troese MJ, Sarkar M, Galloway NL, et al. Differential expression and glycosylation of Anaplasma phagocytophilum major surface protein 2 paralogs during cultivation in Sialyl Lewis x-deficient host cells. Infect Immun. 2009; 77(5): 1746–56.
Troese MJ, Carlyon JA. Anaplasma phagocytophilum dense-cored organisms mediate cellular adherence through recognition of human P-selectin glycoprotein ligand 1. Infect Immun. 2009; 77(9): 4018–27.
Fallon BA, Keilp JG, Corbera KM, et al. A randomized, placebo-controlled trial of repeated IV antibiotic therapy for Lyme encephalopathy. Neurology. 2008; 70(13): 992-1003.
Hynes WL, Stokes MM, Hensley SM, et al. Using RNA interference to determine the role of varisin in the innate immune system of the hard tick Dermacentor variabilis (Acari: Ixodidae). Exp Appl Acarol. 2008; 46(1-4): 7-15
Kocan KM, de la Fuente J, Manzano-Roman R, et al. Silencing expression of the defensin, varisin, in male Dermacentor variabilis by RNA interference results in reduced Anaplasma marginale infections. Exp Appl Acarol. 2008;46(1-4):17-28.
Nelson CM, Herron MJ, Felsheim RF et al. Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics. 2008; 9: 364
Reneer DV, Troese MJ, Huang BA, et al. Anaplasma phagocytophilum PSGL-1-independent infection does not require Syk and leads to less efficient AnkA delivery. Cell Microbiol. 2008; 10(9): 1827-38.
Sarkar M, Troese MJ, Kearns SA, et al. Anaplasma phagocytophilum MSP2(P44)-18 predominates and is modified into multiple isoforms in human myeloid cells. Infect Immun. 2008; 76(5): 2090–8.
Wickramasekara S, Bunikis J, Wysoki V, Barbour AG. Identification of residual blood proteins in ticks by mass spectrometry proteomics. Emerg Infect Dis. 2008; 14(8): 1273-5.
Sarkar M, Reneer DV, Carlyon JA. Sialyl-Lewis x-independent infection of human myeloid cells by Anaplasma phagocytophilum strains HZ and HGE1. Infect Immun. 2007; 75(12): 5720-5.
Keilp JG, Corbera K, Slavov I, et al. WAIS-III and WMS-III performance in chronic Lyme disease. J Int Neuropsychol Soc. 2006; 12(1): 119-29.
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